Some difficulties appears when you want using GoogleMaps with street view and "Yellow little guy" (see thumbnail), when the Adguard Assistant in "ON".
This is an example, but i imagine there is other case like this.
An option is to put an "on/off"button on the first principal window below...
Especially https filtering breaks quite a few apps, way more than whitelisted by default and that will probably always be the case.
Examples I found after a single day of usage:
Google Play Newsstand - downloading purchased magazines is impossible with https filtering active.