Interesting. I don't use Adguard to block ads on Windows 10 except with Windows Apps. However, I don't use a Windows Store apps that are website apps. I prefer the browserUnfortunately for me, the reason I notice it is because suddenly I will start seeing ads again in my browser. I check the tray icon and it is gone. Haven't checked to see if it is still running in Task Manager, but if it isn't blocking ads then it is useless.
I use Adguard on Windows to help block possible malicious websites. Like Malwarebytes, Adguard uses a different methodology than Bitdefender for blocking potentially malicious websites. My understanding is that Malwarebytes and Adgurd use malicious website lists to block potentially malicious websites. Bitdefender uses a different method. Since along email spam malicious websites are the main sources of malware I like to have a second opinion to help block potential malicious websites.
Since I use Firefox as my browser on W10 and I can use the Firefox add-on, Bluhell Firewall to block ads. It works great. It also blocks some malicious websites.
I don't think there is a conflict between Adguard and Bluhell Firewall because the majority of Adguard crashes by far have been when I was not using W10 and Firefox was closed.