Due to the MySQL issue i switched Adguard to act as a proxy (http://forum.adguard.com/showthread.php?4450-Adguard-causing-MySQL-connections-to-fail)
Now I randomly encounter proxy errors claiming that the website is not available. A reload of the website (F5) fixes this issue all the time.
It is not really reproducible, if a page that errored out previously is requested a second time it usually works.
I noticed it a couple of times while clicking through a slide show like:
http://www.heise.de/autos/artikel/Reportage-24-Stunden-von-Le-Mans-2015-2557289.html?view=bildergalerie
Version: 5.10.1190.6188
Browser: Opera/28.0.1750.31 (Edition beta) based on Chrome/41.0.2272.53
Screenshot:

Stacktrace:
Now I randomly encounter proxy errors claiming that the website is not available. A reload of the website (F5) fixes this issue all the time.
It is not really reproducible, if a page that errored out previously is requested a second time it usually works.
I noticed it a couple of times while clicking through a slide show like:
http://www.heise.de/autos/artikel/Reportage-24-Stunden-von-Le-Mans-2015-2557289.html?view=bildergalerie
Version: 5.10.1190.6188
Browser: Opera/28.0.1750.31 (Edition beta) based on Chrome/41.0.2272.53
Screenshot:

Stacktrace:
Code:
System.Net.ProtocolViolationException: Line cannot be empty
Source: Adguard.HttpStack
trace:
at Adguard.Http.Protocol.HttpBaseStatusLine..ctor(Byte[] lineBytes)
at Adguard.Http.Protocol.HttpResponse.ParseStatusLine(Byte[] statusLine)
at Adguard.Http.Protocol.HttpBase.ParseStatusLine(Stream stream)
at Adguard.Http.Protocol.HttpBase..ctor(Stream stream)
at Adguard.Proxy.Http.HttpProxyServer.GetHttpResponse(HttpProxyConnectionContext context, Stream remoteStream)
at Adguard.Proxy.Http.HttpProxyServer.ProcessHttpRequest(HttpRequest request, HttpProxyConnectionContext context)
at Adguard.Proxy.Http.HttpProxyServer.ProcessConnection(TcpConnectionContext context)